Shigeru Abe Selected Research

Tea Tree Oil

1/2013	Suppression of inflammatory reactions by terpinen-4-ol, a main constituent of tea tree oil, in a murine model of oral candidiasis and its suppressive activity to cytokine production of macrophages in vitro.
1/2013	[Effects of inhibitory activity on mycelial growth of Candida albicans and therapy for murine oral candidiasis by the combined use of terpinen-4-ol and a middle-chain fatty acid, capric acid].
1/2012	The essential oil of Melaleuca alternifolia (tea tree oil) and its main component, terpinen-4-ol protect mice from experimental oral candidiasis.

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Shigeru Abe Research Topics

Disease

20	Oral Candidiasis (Thrush) 01/2015 - 01/2003
19	Candidiasis (Moniliasis) 01/2016 - 01/2003
13	Infections 01/2017 - 01/2003
7	Inflammation (Inflammations) 01/2016 - 10/2005
4	Neoplasms (Cancer) 09/2022 - 01/2003
4	Edema (Dropsy) 01/2012 - 10/2005
2	Neoplasm Metastasis (Metastasis) 09/2022 - 06/2008
2	Tinea Pedis (Athlete's Foot) 01/2021 - 01/2007
2	Body Weight (Weight, Body) 01/2012 - 06/2008
1	Carcinoma (Carcinomatosis) 09/2022
1	Fibrosarcoma 09/2022
1	Tinea (Ringworm) 01/2017
1	Onychomycosis (Tinea Unguium) 02/2016
1	Otitis 01/2012
1	Lewis Lung Carcinoma 06/2008
1	Invasive Pulmonary Aspergillosis 12/2006
1	Experimental Arthritis 01/2006
1	Xerostomia 01/2004
1	Diabetes Mellitus 01/2004
1	Mycoses (Diseases, Fungus) 01/2004
1	Cardiomyopathies (Cardiomyopathy) 11/2003
1	Cardiac Arrhythmias (Arrythmia) 11/2003
1	Myocardial Infarction 07/2003
1	Ischemia 07/2003
1	Spasm (Spasms) 07/2003

Drug/Important Bio-Agent (IBA)

7	Antifungal AgentsIBA 01/2017 - 01/2003
6	Volatile Oils (Essential Oils)IBA 01/2021 - 10/2005
4	Itraconazole (Sporanox)FDA LinkGeneric 01/2017 - 12/2006
4	Therapeutic UsesIBA 01/2017 - 01/2010
4	LactoferrinIBA 06/2004 - 08/2003
3	decanoic acid (capric acid)IBA 01/2015 - 01/2012
3	Tea Tree OilIBA 01/2013 - 01/2012
3	CytokinesIBA 01/2013 - 01/2004
3	Peroxidase (Myeloperoxidase)IBA 01/2013 - 01/2006
3	terpinenol-4IBA 01/2013 - 01/2012
2	Liposomes (Liposome)IBA 09/2022 - 01/2003
2	Pharmaceutical PreparationsIBA 09/2022 - 03/2012
2	PowdersIBA 01/2015 - 09/2006
2	Drinking WaterIBA 01/2015 - 08/2003
2	oligonolIBA 01/2015 - 01/2010
2	AcetylglucosamineIBA 01/2015 - 04/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2013 - 01/2012
2	FarnesolIBA 11/2012 - 07/2008
2	AzolesIBA 03/2012 - 01/2012
2	liranaftateIBA 01/2012 - 01/2010
2	phorbolIBA 01/2012 - 01/2010
2	polyglucosanIBA 01/2012 - 10/2005
2	ThiocarbamatesIBA 01/2012 - 01/2010
2	cinnamaldehyde (cinnamic aldehyde)FDA Link 01/2012 - 01/2011
2	Prednisolone (Predate)FDA LinkGeneric 01/2012 - 06/2004
2	Plant Preparations (Preparation, Plant)IBA 01/2010 - 01/2004
2	Beclomethasone (Beclometasone)FDA Link 02/2008 - 03/2007
2	Hypnotics and Sedatives (Sedatives)IBA 01/2007 - 01/2003
2	Milk Proteins (Milk Protein)IBA 06/2004 - 08/2003
1	mifamurtideIBA 09/2022
1	Antineoplastic Agents (Antineoplastics)IBA 09/2022
1	Fluorouracil (Carac)FDA LinkGeneric 09/2022
1	phosphatidylethanolamineIBA 09/2022
1	PicibanilIBA 09/2022
1	Terbinafine (Lamisil)FDA LinkGeneric 01/2017
1	2- (3,5- dimethyl- 1H- pyrazol- 1- yl)- 5- methylphenolIBA 02/2016
1	Food IngredientsIBA 01/2014
1	TrypsinIBA 11/2012
1	Glucose (Dextrose)FDA LinkGeneric 04/2012
1	Fluconazole (Zonal)FDA LinkGeneric 01/2012
1	Immunoglobulin A (IgA)IBA 01/2012
1	p-Methoxy-N-methylphenethylamineIBA 01/2012
1	Methylcellulose (BFL)IBA 01/2011
1	Food Additives (Food Additive)IBA 01/2011
1	EnzymesIBA 01/2010
1	PolyphenolsIBA 01/2010
1	TeaIBA 01/2010
1	geraniol (nerol)IBA 08/2008
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 06/2008
1	InterferonsIBA 06/2008
1	GlucocorticoidsIBA 02/2008
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2007
1	CyclodextrinsIBA 02/2007
1	hydroxyitraconazoleIBA 02/2007
1	hydroxide ionIBA 02/2007
1	SolutionsIBA 02/2007
1	SaltsIBA 01/2007
1	Chlorpromazine (Thorazine)FDA Link 01/2007
1	2-Hydroxypropyl-beta-cyclodextrinIBA 12/2006
1	Interferon-gamma (Interferon, gamma)IBA 09/2006
1	CollagenIBA 01/2006
1	CarrageenanIBA 01/2006
1	curdlanIBA 10/2005
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2004
1	Clove Oil (Oil of Cloves)IBA 01/2004
1	Octreotide (Sandostatin)FDA LinkGeneric 11/2003
1	Ergonovine (Ergometrine)IBA 07/2003

Therapy/Procedure

9	Oral Administration 01/2016 - 01/2003
5	Therapeutics 01/2014 - 01/2003
1	Induced Hyperthermia (Thermotherapy) 01/2007
1	Intravenous Administration 12/2006
1	Intraperitoneal Injections 01/2006
1	Aromatherapy 01/2006
1	Immunotherapy 06/2004
1	Oral Hygiene (Dental Hygiene) 01/2004